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Cell signaling news

Here we present recent news items specially selected from Nature, Nature Medicine, Nature Biotechnology and Nature Reviews Drug Discovery.

November 2008

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News | News in brief | News Features

News

Mice share yeast's ageing system
Studies in mice suggest that the sirtuitin proteins, which regulate lifespan in yeast by protecting its genome, may perform the same function in mammals.
Nature News (27 November 2008)
| Full Text |

Web data predict flu
Two research teams have successfully detected the onset of US seasonal flu epidemics by extracting patterns of flu-related search terms from the billions of queries stored by Google and Yahoo.
Nature News (20 November 2008)
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Gene testing of embryos needs guiding
Genetic analyses that use 'SNP chips' could potentially be used to estimate an embryo's risk of adult-onset diseases and other traits, such as hair, eye and skin color.
Nature News (20 November 2008)
| Full Text |

Obesity linked to grandparental diet
Mice fed on a high-fat diet throughout their pregnancies and suckling had offspring that were larger than normal — a trait that was, surprisingly, also passed on to their offspring's offspring.
Nature News (20 November 2008)
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Scientists self-censor after political attack
Scientists whose work came under scrutiny during a political debate about work funded by the US National Institutes of Health (NIH) censored their own later work.
Nature News (18 November 2008)
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Science in the meltdown
Scientific research faces many uncertainties in the looming global recession — but it also has many strengths that may help it weather the storm.
Nature News (13 November 2008)
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Company sues researcher over unfavourable review
A biomedical researcher at the US National Institutes of Health has been sued by the pharmacological company Biopure for publishing a study that linked a class of blood substitutes to increased risk of heart attack and death.
Nature News (11 November 2008)
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Gene-testing company fights to retain listing
Beleaguered genomics company deCODE Genetics of Reykjavik, Iceland, is preparing to plead its case to prevent it from being delisted from the NASDAQ stock exchange.
Nature News (11 November 2008)
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Should healthy people take statins too?
Rosuvastatin appears to lower the risk of heart disease in healthy people.
Nature News (10 November 2008)
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India partners to fast track biotech
India is embarking on a series of collaborations — including a £160 million partnership between the London-based Wellcome Trust and India's Department of Biotechnology — to boost research and train manpower for its burgeoning biotech industry.
Nature Biotechnology (November 2008)
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FDA cracks down on labeling, initiates trial result reporting
In accordance with the US Food and Drug Administration Amendments Act (FDAAA), the US National Institutes of Health's publicly available database has expanded to track the results of human drug trials.
Nature Biotechnology (November 2008)
| Full Text |

US researchers await key science appointments by next president
US president-elect Barack Obama's choice of officials, such as the presidential science advisor, the secretary of Health and Human Services and the director of the National Institutes of Health (NIH), will serve as an indication of the policies that researchers can expect for the next four years.
Nature Medicine (November 2008)
| Full Text |

China takes first steps toward healthcare and drug reforms
In the wake of a bribery scandal and a disastrous baby formula recall, Chinese leaders are carrying out a slew of healthcare reforms.
Nature Medicine (November 2008)
| Full Text |

India plans for interdisciplinary neuroscience research center
The Indian Institute of Science in Bangalore has approved a new multidisciplinary neuroscience research center, which will host experts from departments as varied as electrical communication engineering, computer sciences, mathematics and chemistry.
Nature Medicine (November 2008)
| Full Text |

Safer stem cells
Scientists have developed a new way to generate induced pluripotent stem (iPS) cells using a heavily modified version of the common cold virus, which may potentially sidestep the viral hazards thought to plague earlier generations of stem cell lines.
Nature Medicine (November 2008)
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Geneticists crack the code of infertility
Researchers have uncovered several genetic mutations that may contribute to infertility.
Nature Medicine (November 2008)
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Industry shifts focus to immunology and cancer
Cardiology and anemia lose out in the hunt for the next pharmaceutical blockbusters.
Nature News (6 November 2008)
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Human genes are multitaskers
Genome-wide surveys of gene expression in 15 different tissues and cell lines have revealed that up to 94% of human genes generate more than one product.
Nature News (6 November 2008)
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How to get the most from a gene test
New start-ups and services are now developing ways to improve the limited value of information provided by personal genomics companies for consumers and scientists alike.
Nature News (6 November 2008)
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Genomics takes hold in Asia
Genome Institute of Singapore head Edison Liu talks about how to make pan-Asian genomics research projects work.
Nature News (6 November 2008)
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Pathways to cancer therapy
New studies have affirmed the complexity of genetic changes in solid tumors, but also revealed commonalities in the associated pathways, suggesting that a pathway-oriented perspective could aid cancer drug discovery and therapy.
Nature Reviews Drug Discovery (November 2008)
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News in brief

| Unique collaborations at Howard Hughes institute | Drug giant shows its commitment to stem cells | US drug agency opens outposts in China | WHO congress backs traditional medicine | Proposed reform to animal testing rules draws fire | Contaminants identified in plastic lab equipment | Research agency focuses on first-time applicants | Billion-dollar bid for stem-cell treatments | Deaths stalk GLP-1 agonist | Google settles suit over copyright of scanned books | Pathways to aid translation

News Features

Argentina: The come back
After winning the Argentinean presidential election in October 2007, Cristina Fernández de Kirchner has fought to reverse a decades-long scientific 'brain drain' by hiring a science minister, building new research facilities and increasing the budget for competitive research grants.
Nature News (27 November 2008)
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Neuroscience: The plaque plan
Nature investigates why the wealth of knowledge about Alzheimer's disease pathophysiology has not yet translated to a cure, and what can be done to hasten the development of effective therapeutics.
Nature News (13 November 2008)
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Breaching the barrier
Armed with new information about the biology of the blood-brain barrier and several new drug-delivery approaches, pharmaceutical companies are starting to tackle the age-old problem of how to deliver neurological treatments directly to the brain.
Nature News (November 2008)
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Personal genomes: The case of the missing heritability
When scientists opened up the human genome, they expected to find the genetic components of common traits and diseases but they were nowhere to be seen. Brendan Maher shines a light on six places where the missing loot could be stashed away.
Nature News (6 November 2008)
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Personal genomes: Standard and pores
Could the next generation of genetic sequencing machines be built from a collection of minuscule holes?
Nature News (6 November 2008)
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Personal genomes: A disruptive personality, disrupted
Eric Schadt, executive scientific director of research genetics for Rosetta Inpharmatics, hopes to charge ahead in the face of his company's disintegration.
Nature News (6 November 2008)
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 Nature Publishing Group

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