Research library: Lipid signaling
2008:
| December
| November
| October
| September
| August
| July
| June
| May
| April
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007
December
letter
Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases
M Melina Soares, Steven W King & Philip E Thorpe
Nature Medicine 14, 1357–1362
(December 2008); doi:10.1038/nm.1885
| Summary | Full Text (HTML / PDF) |
article
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation
Victoria Marsh et al.
Nature Genetics 40, 1436–1444
(December 2008); doi:10.1038/ng.256
| Summary | Full Text (HTML / PDF) |
November
article
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases
Beth Apsel et al.
Nature Chemical Biology 4, 691–699
(November 2008); doi:10.1038/nchembio.117
| Summary | Full Text (HTML / PDF) |
news and views
Killing two kinase families with one stone
Benoit Bilanges, Neil Torbett & Bart Vanhaesebroeck
Nature Chemical Biology 4, 648–649
(November 2008); doi:10.1038/nchembio1108-648
| Full Text (HTML / PDF) |
article
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
Rene O Sanchez-Mejia et al.
Nature Neuroscience 11, 1311–1318
(November 2008); doi:10.1038/nn.2213
| Summary | Full Text (HTML / PDF) |
October
article
A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P2
Avia Rosenhouse-Dantsker et al.
Nature Chemical Biology 4, 624–631
(October 2008); doi:10.1038/nchembio.112
| Summary | Full Text (HTML / PDF) |
article
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance
Jia-Shu Yang et al.
Nature Cell Biology 10, 1146–1153
(October 2008); doi:10.1038/ncb1774
| Summary | Full Text (HTML / PDF) |
article
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
Robert L Wilensky et al.
Nature Medicine 14, 1059–1066
(October 2008); doi:10.1038/nm.1870
| Summary | Full Text (HTML / PDF) |
news and views
Getting to the core of atherosclerosis
Nancy R Webb
Nature Medicine 14, 1015–1016
(October 2008); doi:10.1038/nm1008-1015
| Full Text (HTML / PDF) |
September
article
Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation
Rémi Lasserre et al.
Nature Chemical Biology 4, 538–547
(September 2008); doi:10.1038/nchembio.103
| Summary | Full Text (HTML / PDF) |
progress
Structural comparisons of class I phosphoinositide 3-kinases
L. Mario Amzel et al.
Nature Reviews Cancer 8, 665–669
(September 2008); doi:10.1038/nrc2443
| Summary | Full Text (HTML / PDF) |
August
review
Shaping cups into phagosomes and macropinosomes
Joel A. Swanson
Nature Reviews Molecular Cell Biology 9, 639–649
(August 2008); doi:10.1038/nrm2447
| Summary | Full Text (HTML / PDF) |
letter
Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis
Shidong Jia et al.
Nature 454, 776–779
(7 August 2008); doi:10.1038/nature07091
| Summary | Full Text (HTML / PDF) |
brief communication
Control of thermotactic behavior via coupling of a TRP channel to a phospholipase C signaling cascade
Young Kwon, Hye-Seok Shim, Xiaoyue Wang & Craig Montell
Nature Neuroscience 11, 871–873
(August 2008); doi:10.1038/nn.2170
| Summary | Full Text (HTML / PDF) |
July
letter
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Ignacio Varela et al.
Nature Medicine 14, 767–772
(July 2008); doi:10.1038/nm1786
| Summary | Full Text (HTML / PDF) |
news and views
Rejuvenating premature aging
Eran Meshorer & Yosef Gruenbaum
Nature Medicine 14, 713–715
(July 2008); doi:10.1038/nm0708-713
| Full Text (HTML / PDF) |
review
Membrane fusion
William Wickner & Randy Schekman
Nature Structural & Molecular Biology 15, 658–664
(July 2008); doi:10.1038/nsmb.1451
| Summary | Full Text (HTML / PDF) |
article
Complexin and Ca2+ stimulate SNARE-mediated membrane fusion
Tae-Young Yoon et al.
Nature Structural & Molecular Biology 15, 707–713
(July 2008); doi:10.1038/nsmb.1446
| Summary | Full Text (HTML / PDF) |
June
article
Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms
Christoph Buettner et al.
Nature Medicine 14, 667–675
(June 2008); doi:10.1038/nm1775
| Summary | Full Text (HTML / PDF) |
news and views
The long reach of leptin
Eleftheria Maratos-Flier
Nature Medicine 14, 604–606
(June 2008); doi:10.1038/nm0608-604
| Full Text (HTML / PDF) |
review
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
Masato Furuhashi & Gökhan S. Hotamisligil
Nature Reviews Drug Discovery 7, 489–503
(June 2008); doi:10.1038/nrd2589
| Summary | Full Text (HTML / PDF) |
review
Multiple roles for lipids in the Hedgehog signalling pathway
Suzanne Eaton
Nature Reviews Molecular Cell Biology 9, 437–445
(June 2008); doi:10.1038/nrm2414
| Summary | Full Text (HTML / PDF) |
May
letter
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
Yi Guo et al.
Nature 453, 657–661
(29 May 2008); doi:10.1038/nature06928
| Summary | Full Text (HTML / PDF) |
review
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme, Joseph V. Virbasius, Vishwajeet Puri & Michael P. Czech
Nature Reviews Molecular Cell Biology 9, 367–377
(May 2008); doi:10.1038/nrm2391
| Summary | Full Text (HTML / PDF) |
review
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Charles N. Serhan, Nan Chiang & Thomas E. Van Dyke
Nature Reviews Immunology 8, 349–361
(May 2008); doi:10.1038/nri2294
| Summary | Full Text (HTML / PDF) |
article
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
Linda V Sinclair et al.
Nature Immunology 9, 513–521
(May 2008); doi:10.1038/ni.1603
| Summary | Full Text (HTML / PDF) |
news and views
Moving out: mobilizing activated T cells from lymphoid tissues
Gabriel Berstein & Robert T Abraham
Nature Immunology 9, 455–457
(May 2008); doi:10.1038/ni0508-455
| Full Text (HTML / PDF) |
article
Oligomeric amyloid-β peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism
Diego E Berman et al.
Nature Neuroscience 11, 547–554
(May 2008); doi:10.1038/nn.2100
| Summary | Full Text (HTML / PDF) |
April
article
Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering
Philipp Mueller et al.
Nature Immunology 9, 424–431
(April 2008); doi:10.1038/ni1570
| Summary | Full Text (HTML / PDF) |
February
review
Inositol derivatives: evolution and functions
Robert H. Michell
Nature Reviews Molecular Cell Biology 9, 151–161
(February 2008); doi:10.1038/nrm2334
| Summary | Full Text (HTML / PDF) |
article
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
Xiaoyong Yang et al.
Nature 451, 964–969
(21 February 2008); doi:10.1038/nature06668
| Summary | Full Text (HTML / PDF) |
letter
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
David L. Mellman et al.
Nature 451, 1013–1017
(21 February 2008); doi:10.1038/nature06666
| Summary | Full Text (HTML / PDF) |
review
Cellular cholesterol trafficking and compartmentalization
Elina Ikonen
Nature Reviews Molecular Cell Biology 9, 125–138
(February 2008); doi:10.1038/nrm2336
| Summary | Full Text (HTML / PDF) |
letter
Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels
Yanping Xu, Yajamana Ramu & Zhe Lu
Nature 451, 826–829
(14 February 2008); doi:10.1038/nature06618
| Summary | Full Text (HTML / PDF) |
review
Membrane lipids: where they are and how they behave
Gerrit van Meer, Dennis R. Voelker & Gerald W. Feigenson
Nature Reviews Molecular Cell Biology 9, 112–124
(February 2008); doi:10.1038/nrm2330
| Summary | Full Text (HTML / PDF) |
review
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun & Lina M. Obeid
Nature Reviews Molecular Cell Biology 9, 139–150
(February 2008); doi:10.1038/nrm2329
| Summary | Full Text (HTML / PDF) |
scientific report
A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding
Harold B J Jefferies et al.
EMBO Reports 9, 164–170
(February 2008); doi:10.1038/sj.embor.7401155
| Summary | Full Text (HTML / PDF) |
review
Membrane recognition by phospholipid-binding domains
Mark A. Lemmon
Nature Reviews Molecular Cell Biology 9, 99–111
(February 2008); doi:10.1038/nrm2328
| Summary | Full Text (HTML / PDF) |
review
Lipid signalling in disease
Matthias P. Wymann & Roger Schneiter
Nature Reviews Molecular Cell Biology 9, 162–176
(February 2008); doi:10.1038/nrm2335
| Summary | Full Text (HTML / PDF) |
January
news and views
IP7 guards the CDK gate
John D York & Daniel J Lew
Nature Chemical Biology 4, 16–17
(January 2008); doi:10.1038/nchembio0108-16
| Full Text (HTML / PDF) |
article
ARF1 is directly involved in dynamin-independent endocytosis
Sudha Kumari & Satyajit Mayor
Nature Cell Biology 10, 30–41
(January 2008); doi:10.1038/ncb1666
| Summary | Full Text (HTML / PDF) |
article
Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13
Geetanjali Bansal, Zhihui Xie, Sudhir Rao, Karl H Nocka & Kirk M Druey
Nature Immunology 9, 73–80
(January 2008); doi:10.1038/ni1533
| Summary | Full Text (HTML / PDF) |
letter
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
Lao H Saal et al.
Nature Genetics 40, 102–107
(January 2008); doi:10.1038/ng.2007.39
| Summary | Full Text (HTML / PDF) |
news and views
BRCA1—sowing the seeds crooked in the furrow
William D Foulkes
Nature Genetics 40, 8–9
(January 2008); doi:10.1038/ng0108-8
| Full Text (HTML / PDF) |
article
Molecular basis of cyclin–CDK–CKI regulation by reversible binding of an inositol pyrophosphate
Young-Sam Lee, Kexin Huang, Florante A Quiocho & Erin K O'Shea
Nature Chemical Biology 4, 25–32
(January 2008); doi:10.1038/nchembio.2007.52
| Summary | Full Text (HTML / PDF) |
|
