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Research library: Membrane traffic

2008: | December | November | October | September | August | July | May | April | March | February | January

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letter
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
Bernard T. Kelly et al.
Nature 456, 976–979
(18 December 2008); doi:10.1038/nature07422
| Summary | Full Text (HTML / PDF) |

review
VPS10P-domain receptors — regulators of neuronal viability and function
Thomas E. Willnow, Claus M. Petersen & Anders Nykjaer
Nature Reviews Neuroscience 9, 899–909
(December 2008); doi:10.1038/nrn2516
| Summary | Full Text (HTML / PDF) |

article
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
Boyoun Park et al.
Nature Immunology 9, 1407–1414
(December 2008); doi:10.1038/ni.1669
| Summary | Full Text (HTML / PDF) |

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Sarah E. Ewald et al.
Nature 456, 658–662
(04 December 2008); doi:10.1038/nature07405
| Summary | Full Text (HTML / PDF) |

article
CD15 expression in human myeloid cell differentiation is regulated by sialidase activity
Samah Zeineb Gadhoum & Robert Sackstein
Nature Chemical Biology 4, 751–757
(December 2008); doi:10.1038/nchembio.116
| Summary | Full Text (HTML / PDF) |

news and views
Seeing cellular sialidase transform sugars
Minoru Fukuda & Xingfeng Bao
Nature Chemical Biology 4, 721–722
(December 2008); doi:10.1038/nchembio1208-721
| Full Text (HTML / PDF) |

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Scaffolding function of PAK in the PDK1–Akt pathway
Maiko Higuchi, Keisuke Onishi, Chikako Kikuchi & Yukiko Gotoh
Nature Cell Biology 10, 1356–1364
(November 2008); doi:10.1038/ncb1795
| Summary | Full Text (HTML / PDF) |

review
Derailed endocytosis: an emerging feature of cancer
Yaron Mosesson, Gordon B. Mills & Yosef Yarden
Nature Reviews Cancer 8, 835–850
(November 2008); doi:10.1038/nrc2521
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article
KIF1Bβ- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD
Shinsuke Niwa, Yosuke Tanaka & Nobutaka Hirokawa
Nature Cell Biology 10, 1269-1279 (2008)
(November 2008); doi:10.1038/ncb1785
| Summary | Full Text (HTML / PDF) |

review
Coordinated protein sorting, targeting and distribution in polarized cells
Ira Mellman & W. James Nelson
Nature Reviews Molecular Cell Biology 9, 833–845
(November 2008); doi:10.1038/nrm2525
| Summary | Full Text (HTML / PDF) |

review
Silent synapses and the emergence of a postsynaptic mechanism for LTP
Geoffrey A. Kerchner & Roger A. Nicoll
Nature Reviews Neuroscience 9, 813–825
(November 2008); doi:10.1038/nrn2501
| Summary | Full Text (HTML / PDF) |

review
Phagosome maturation: going through the acid test
Jason M. Kinchen & Kodi S. Ravichandran
Nature Reviews Molecular Cell Biology 9, 781–795
(October 2008); doi:10.1038/nrm2515
| Summary | Full Text (HTML / PDF) |

article
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance
Jia-Shu Yang et al.
Nature Cell Biology 10, 1146–1153
(October 2008); doi:10.1038/ncb1774
| Summary | Full Text (HTML / PDF) |

letter
The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network
Min Sup Song et al.
Nature 455, 813–817
(9 October 2008); doi:10.1038/nature07290
| Summary | Full Text (HTML / PDF) |

letter
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes
Daisuke Satoh et al.
Nature Cell Biology 10, 1164–1171
(October 2008); doi:10.1038/ncb1776
| Summary | Full Text (HTML / PDF) |

letter
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons
Yi Zheng et al.
Nature Cell Biology 10, 1172–1180
(October 2008); doi:10.1038/ncb1777
| Summary | Full Text (HTML / PDF) |

news and views
Dynein branches out
Guy Tear
Nature Cell Biology 10, 1131–1132
(October 2008); doi:10.1038/ncb1008-1131
| Full Text (HTML / PDF) |

letter
A canine DNM1 mutation is highly associated with the syndrome of exercise-induced collapse
Edward E Patterson et al.
Nature Genetics 40, 1235–1239
(October 2008); doi:10.1038/ng.224
| Summary | Full Text (HTML / PDF) |

letter
UNC-6/netrin and its receptor UNC-5 locally exclude presynaptic components from dendrites
Vivian Y. Poon, Matthew P. Klassen & Kang Shen
Nature 455, 669–673
(2 October 2008); doi:10.1038/nature07291
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brief communication
MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity
Thomas Müller et al.
Nature Genetics 40, 1163–1165
(October 2008); doi:10.1038/ng.225
| Summary | Full Text (HTML / PDF) |

letter
FcRn-mediated antibody transport across epithelial cells revealed by electron tomography
Wanzhong He et al.
Nature 455, 542–546
(25 September 2008); doi:10.1038/nature07255
| Summary | Full Text (HTML / PDF) |

article
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking
Michel C Van den Oever et al.
Nature Neuroscience 11, 1053–1058
(September 2008); doi:10.1038/nn.2165
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article
Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation
Rémi Lasserre et al.
Nature Chemical Biology 4, 538–547
(September 2008); doi:10.1038/nchembio.103
| Summary | Full Text (HTML / PDF) |

article
SRP RNA controls a conformational switch regulating the SRP–SRP receptor interaction
Saskia B Neher, Niels Bradshaw, Stephen N Floor, John D Gross & Peter Walter
Nature Structural & Molecular Biology 15, 916–923
(September 2008); doi:10.1038/nsmb.1467
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article
Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors
Clara L Essmann et al.
Nature Neuroscience 11, 1035–1043
(September 2008); doi:10.1038/nn.2171
| Summary | Full Text (HTML / PDF) |

article
Misfolded proteins partition between two distinct quality control compartments
Daniel Kaganovich, Ron Kopito & Judith Frydman
Nature 454, 1088–1095
(28 August 2008); doi:10.1038/nature07195
| Summary | Full Text (HTML / PDF) |

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Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
Subba Rao Gangi Setty et al.
Nature 454, 1142–1146
(28 August 2008); doi:10.1038/nature07163
| Summary | Full Text (HTML / PDF) |

letter
Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea
Daniel D. Shaye, Jordi Casanova & Marta Llimargas
Nature Cell Biology 10, 964–970
(August 2008); doi:10.1038/ncb1756
| Summary | Full Text (HTML / PDF) |

article
Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes
Arnauld Sergé, Nicolas Bertaux, Hervé Rigneault & Didier Marguet
Nature Methods 5, 687–694
(August 2008); doi:10.1038/nmeth.1233
| Summary | Full Text (HTML / PDF) |

brief communication
The stress hormone corticosterone conditions AMPAR surface trafficking and synaptic potentiation
Laurent Groc, Daniel Choquet & Francis Chaouloff
Nature Neuroscience 11, 868–870
(August 2008); doi:10.1038/nn.2150
| Summary | Full Text (HTML / PDF) |

perspective
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
Stefan Schütze, Vladimir Tchikov & Wulf Schneider-Brachert
Nature Reviews Molecular Cell Biology 9, 655–662
(August 2008); doi:10.1038/nrm2430
| Summary | Full Text (HTML / PDF) |

article
A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway
Teodoro Pulvirenti et al.
Nature Cell Biology 10, 912–922
(August 2008); doi:10.1038/ncb1751
| Summary | Full Text (HTML / PDF) |

news and views
Golgi gets wired up
Lennart Asp & Tommy Nilsson
Nature Cell Biology 10, 885–887
(August 2008); doi:10.1038/ncb0808-885
| Full Text (HTML / PDF) |

article
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+
Michael C Chicka, Enfu Hui, Huisheng Liu & Edwin R Chapman
Nature Structural & Molecular Biology 15, 827–835
(August 2008); doi:10.1038/nsmb.1463
| Summary | Full Text (HTML / PDF) |

article
Robust single-particle tracking in live-cell time-lapse sequences
Khuloud Jaqaman et al.
Nature Methods 5, 695–702
(August 2008); doi:10.1038/nmeth.1237
| Summary | Full Text (HTML / PDF) |

news and views
Single-particle tracking: connecting the dots
Michael J Saxton
Nature Methods 5, 671–672
(August 2008); doi:10.1038/nmeth0808-671
| Full Text (HTML / PDF) |

review
Mechanisms of membrane fusion: disparate players and common principles
Sascha Martens & Harvey T. McMahon
Nature Reviews Molecular Cell Biology 9, 543–556
(July 2008); doi:10.1038/nrm2417
| Summary | Full Text (HTML / PDF) |

article
Rapid and modifiable neurotransmitter receptor dynamics at a neuronal synapse in vivo
Corey M McCann, Juan Carlos Tapia, Han Kim, Jay S Coggan & Jeff W Lichtman
Nature Neuroscience 11, 807–815
doi:10.1038/nn.2145
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article
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
Tae Joo Park, Brian J Mitchell, Philip B Abitua, Chris Kintner & John B Wallingford
Nature Genetics 40, 871–879
doi:10.1038/ng.104
| Summary | Full Text (HTML / PDF) |

review
Membrane fusion
William Wickner & Randy Schekman
Nature Structural & Molecular Biology 15, 658–664
(July 2008); doi:10.1038/nsmb.1451
| Summary | Full Text (HTML / PDF) |

article
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
Chengyu Liang et al.
Nature Cell Biology 10, 776–787
(July 2008); doi:10.1038/ncb1740
| Summary | Full Text (HTML / PDF) |

news and views
UVRAG reveals its second nature
Karolina Peplowska, Margarita Cabrera & Christian Ungermann
Nature Cell Biology 10, 759–761
(July 2008); doi:10.1038/ncb0708-759
| Full Text (HTML / PDF) |

perspective
Endosomal sorting and signalling: an emerging role for sorting nexins
Peter J. Cullen
Nature Reviews Molecular Cell Biology 9, 574–582
(July 2008); doi:10.1038/nrm2427
| Summary | Full Text (HTML / PDF) |

article
Membrane-dependent signal integration by the Ras activator Son of sevenless
Jodi Gureasko et al.
Nature Structural & Molecular Biology 14, 452–461
(May 2008); doi:10.1038/nsmb.1418
| Summary | Full Text (HTML / PDF) |

review
GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition
Tija C. Jacob, Stephen J. Moss & Rachel Jurd
Nature Reviews Neuroscience 9, 331–343
(May 2008); doi:10.1038/nrn2370
| Summary | Full Text (HTML / PDF) |

review
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy
Lorenzo A. Cingolani & Yukiko Goda
Nature Reviews Neuroscience 9, 344–356
(May 2008); doi:10.1038/nrn2373
| Summary | Full Text (HTML / PDF) |

review
Modification of intracellular membrane structures for virus replication
Sven Miller & Jacomine Krijnse-Locker
Nature Reviews Microbiology 6, 363–374
(May 2008); doi:10.1038/nrmicro1890
| Summary | Full Text (HTML / PDF) |

letter
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
Khalid Al-Nedawi et al.
Nature Cell Biology 10, 619–624
(May 2008); doi:10.1038/ncb1725
| Summary | Full Text (HTML / PDF) |

article
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Tiziana Di Pucchio et al.
Nature Immunology 9, 551–557
(May 2008); doi:10.1038/ni.1602
| Summary | Full Text (HTML / PDF) |

article
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation
Sven Burgdorf, Christian Schölz, Andreas Kautz, Robert Tampé & Christian Kurts
Nature Immunology 9, 558–566
(May 2008); doi:10.1038/ni.1601
| Summary | Full Text (HTML / PDF) |

news and views
Cross-presentation: avoiding trafficking chaos?
Sudhir Pai Kasturi & Bali Pulendran
Nature Immunology 9, 461–463
(May 2008); doi:10.1038/ni0508-461
| Full Text (HTML / PDF) |

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elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
Yoshihiro Omori et al.
Nature Cell Biology 10, 437–444
(April 2008); doi:10.1038/ncb1706
| Summary | Full Text (HTML / PDF) |

review
Exiting the Golgi complex
Maria Antonietta De Matteis & Alberto Luini
Nature Reviews Molecular Cell Biology 9, 273–284
(April 2008); doi:10.1038/nrm2378
| Summary | Full Text (HTML / PDF) |

article
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
Pamela V Tran et al.
Nature Genetics 40, 403–410
(April 2008); doi:10.1038/ng.105
| Summary | Full Text (HTML / PDF) |

article
Clathrin is a key regulator of basolateral polarity
Sylvie Deborde et al.
Nature 452, 719–723
(10 April 2008); doi:10.1038/nature06828
| Summary | Full Text (HTML / PDF) |

news and views
Cell biology: Porter and sorter
Michael G. Roth
Nature 452, 706–707
(10 April 2008); doi:10.1038/452706a
| Full Text (HTML / PDF) |

article
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira & Ruslan Medzhitov
Nature Immunology 9, 361–368
(April 2008); doi:10.1038/ni1569
| Summary | Full Text (HTML / PDF) |

news and views
Location, location, location: identifying the neighborhoods of LPS signaling
Colin Watts
Nature Immunology 9, 343–345
(April 2008); doi:10.1038/ni0408-343
| Full Text (HTML / PDF) |

article
Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation
Susana S Correia et al.
Nature Neuroscience 11, 457–466
(April 2008); doi:10.1038/nn2063
| Summary | Full Text (HTML / PDF) |

article
Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis
Daniel L. Rocca, Stéphane Martin, Emma L. Jenkins & Jonathan G. Hanley
Nature Cell Biology 10, 259–271
(March 2008); doi:10.1038/ncb1688
| Summary | Full Text (HTML / PDF) |

letter
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim, Melanie M. Brinkmann, Marie-Eve Paquet & Hidde L. Ploegh
Nature 452, 234–238
(13 March 2008); doi:10.1038/nature06726
| Summary | Full Text (HTML / PDF) |

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Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity
Shuzhen Men et al.
Nature Cell Biology 10, 237–244
(February 2008); doi:10.1038/ncb1686
| Summary | Full Text (HTML / PDF) |

review
Cellular cholesterol trafficking and compartmentalization
Elina Ikonen
Nature Reviews Molecular Cell Biology 9, 125–138
(February 2008); doi:10.1038/nrm2336
| Summary | Full Text (HTML / PDF) |

letter
Co-option of a default secretory pathway for plant immune responses
Chian Kwon et al.
Nature 451, 835–840
(14 February 2008); doi:10.1038/nature06545
| Summary | Full Text (HTML / PDF) |

review
Membrane lipids: where they are and how they behave
Gerrit van Meer, Dennis R. Voelker & Gerald W. Feigenson
Nature Reviews Molecular Cell Biology 9, 112–124
(February 2008); doi:10.1038/nrm2330
| Summary | Full Text (HTML / PDF) |

review
Phagocytosis and comparative innate immunity: learning on the fly
Lynda M. Stuart & R. Alan Ezekowitz
Nature Reviews Immunology 8, 131–141
(February 2008); doi:10.1038/nri2240
| Summary | Full Text (HTML / PDF) |

scientific report
A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding
Harold B J Jefferies et al.
EMBO Reports 9, 164–170
(February 2008); doi:10.1038/sj.embor.7401155
| Summary | Full Text (HTML / PDF) |

review
Membrane recognition by phospholipid-binding domains
Mark A. Lemmon
Nature Reviews Molecular Cell Biology 9, 99–111
(February 2008); doi:10.1038/nrm2328
| Summary | Full Text (HTML / PDF) |

brief communication
High-density mapping of single-molecule trajectories with photoactivated localization microscopy
Suliana Manley et al.
Nature Methods 5, 155–157
(February 2008); doi:10.1038/nmeth.1176
| Summary | Full Text (HTML / PDF) |

brief communication
Highly inclined thin illumination enables clear single-molecule imaging in cells
Makio Tokunaga, Naoko Imamoto & Kumiko Sakata-Sogawa
Nature Methods 5, 159–161
(February 2008); doi:10.1038/nmeth1171
| Summary | Full Text (HTML / PDF) |

news and views
How the sum of its parts gets greater than the whole
Mario Brameshuber & Gerhard J Schütz
Nature Methods 5, 133–134
(February 2008); doi:10.1038/nmeth0208-133
| Summary | Full Text (HTML / PDF) |

article
Disruption of KIF17–Mint1 interaction by CaMKII-dependent phosphorylation: a molecular model of kinesin–cargo release
Laurent Guillaud, Richard Wong & Nobutaka Hirokawa
Nature Cell Biology 10, 19–29
(January 2008); doi:10.1038/ncb1665
| Summary | Full Text (HTML / PDF) |

news and views
Motor-cargo release: CaMKII as a traffic cop
Shabeen Ally, Amber L. Jolly & Vladimir I. Gelfand
Nature Cell Biology 10, 3–5
(January 2008); doi:10.1038/ncb0108-3
| Summary | Full Text (HTML / PDF) |

article
ARF1 is directly involved in dynamin-independent endocytosis
Sudha Kumari & Satyajit Mayor
Nature Cell Biology 10, 30–41
(January 2008); doi:10.1038/ncb1666
| Summary | Full Text (HTML / PDF) |

review
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery
Kishor M. Wasan, Dion R. Brocks, Stephen D. Lee, Kristina Sachs-Barrable & Sheila J. Thornton
Nature Reviews Drug Discovery 7, 84–99
(January 2008); doi:10.1038/nrd2353
| Summary | Full Text (HTML / PDF) |

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