Research library: Diabetes / Obesity
2008:
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Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007
December
letter
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
Theresa Alenghat et al.
Nature 456, 997–1000
(18 December 2008); doi:10.1038/nature07541
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news and views
Circadian clocks: Tips from the tip of the iceberg
Fred W. Turek
Nature 456, 881–883
(18 December 2008); doi:10.1038/456881a
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article
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells
Thomas F.J. Wagner et al.
Nature Cell Biology 10, 1421–1430
(December 2008); doi:10.1038/ncb1801
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news and views
A TRP channel-steroid marriage
Bernd Nilius & Thomas Voets
Nature Cell Biology 10, 1383–1384
(December 2008); doi:10.1038/ncb1208-1383
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review
Nutrient sensing and inflammation in metabolic diseases
Gökhan S. Hotamisligil & Ebru Erbay
Nature Reviews Immunology 8, 923–934
(December 2008); doi:10.1038/nri2449
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November
letter
Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity
Alexandra Chadt et al.
Nature Genetics 40, 1354–1359
(November 2008); doi:10.1038/ng.244
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letter
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Yi Liu et al.
Nature 456, 269–273
(13 November 2008); doi:10.1038/nature07349
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review
Metabolic syndrome: from epidemiology to systems biology
Aldons J. Lusis, Alan D. Attie & Karen Reue
Nature Reviews Genetics 9, 819–830
(November 2008); doi:10.1038/nrg2468
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October
letter
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Li Wen et al.
Nature 455, 1109–1113
(23 October 2008); doi:10.1038/nature07336
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review
Sirtuins — novel therapeutic targets to treat age-associated diseases
Siva Lavu, Olivier Boss, Peter J. Elliott & Philip D. Lambert
Nature Reviews Drug Discovery 7, 841–853
(October 2008); doi:10.1038/nrd2665
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review
The insulin paradox: aging, proteotoxicity and neurodegeneration
Ehud Cohen & Andrew Dillin
Nature Reviews Neuroscience 9, 759–767
(October 2008); doi:10.1038/nrn2474
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August
article
PRDM16 controls a brown fat/skeletal muscle switch
Patrick Seale et al.
Nature 454, 961–967
(21 August 2008); doi:10.1038/nature07182
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letter
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng et al.
Nature 454, 1000–1004
(21 August 2008); doi:10.1038/nature07221
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news and views
Developmental biology: Neither fat nor flesh
Barbara Cannon & Jan Nedergaard
Nature 454, 947–948
(21 August 2008); doi:10.1038/454947a
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review
Targeting bile-acid signalling for metabolic diseases
Charles Thomas, Roberto Pellicciari, Mark Pruzanski, Johan Auwerx & Kristina Schoonjans
Nature Reviews Drug Discovery 7, 678–693
(August 2008); doi:10.1038/nrd2619
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July
review
Integration of metabolism and inflammation by lipid-activated nuclear receptors
Steven J. Bensinger & Peter Tontonoz
Nature 454, 470–477
(24 July 2008); doi:10.1038/nature07202
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June
article
Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms
Christoph Buettner et al.
Nature Medicine 14, 667–675
(June 2008); doi:10.1038/nm1775
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news and views
The long reach of leptin
Eleftheria Maratos-Flier
Nature Medicine 14, 604–606
(June 2008); doi:10.1038/nm0608-604
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review
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
Masato Furuhashi & Gökhan S. Hotamisligil
Nature Reviews Drug Discovery 7, 489–503
(June 2008); doi:10.1038/nrd2589
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May
review
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme, Joseph V. Virbasius, Vishwajeet Puri & Michael P. Czech
Nature Reviews Molecular Cell Biology 9, 367–377
(May 2008); doi:10.1038/nrm2391
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April
review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
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review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
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March
article
Variations in DNA elucidate molecular networks that cause disease
Yanqing Chen et al.
Nature 452, 429–435
(27 March 2008); doi:10.1038/nature06757
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review
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
Deborah M. Muoio & Christopher B. Newgard
Nature Reviews Molecular Cell Biology 9, 193–205
(March 2008); doi:10.1038/nrm2327
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review
Hormones of the gut–brain axis as targets for the treatment of upper gastrointestinal disorders
Gareth J. Sanger & Kevin Lee
Nature Reviews Drug Discovery 7, 241–254
(March 2008); doi:10.1038/nrd2444
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February
article
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N Danial et al.
Nature Medicine 14, 144–153
(February 2008); doi:10.1038/nm1717
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article
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
Xiaoyong Yang et al.
Nature 451, 964–969
(21 February 2008); doi:10.1038/nature06668
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letter
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation
Tetsuya Hosooka et al.
Nature Medicine 14, 188–193
(February 2008); doi:10.1038/nm1706
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letter
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim, Junjie Chen & Zhenkun Lou
Nature 451, 583–586
(31 January 2008); doi:10.1038/nature06500
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letter
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu
Nature 451, 587–590
(31 January 2008); doi:10.1038/nature06515
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review
Lipid signalling in disease
Matthias P. Wymann & Roger Schneiter
Nature Reviews Molecular Cell Biology 9, 162–176
(February 2008); doi:10.1038/nrm2335
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