Research library: Cell cycle / DNA repair
2008:
| December
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Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007
December
article
SUMOylation regulates Rad18-mediated template switch
Dana Branzei, Fabio Vanoli & Marco Foiani
Nature 456, 915–920
(18 December 2008); doi:10.1038/nature07587
| Summary | Full Text (HTML / PDF) |
article
The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
Jakob Nilsson, Mona Yekezare, Jeremy Minshull & Jonathon Pines
Nature Cell Biology 10, 1411–1420
(December 2008); doi:10.1038/ncb1799
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news and views
Under arrest in mitosis: Cdc20 dies twice
Andrew M. Fry & Hiroyuki Yamano
Nature Cell Biology 10, 1385–1387
(December 2008); doi:10.1038/ncb1208-1385
| Full Text (HTML / PDF) |
letter
Embryonic stem cell—specific microRNAs regulate the G1-S transition and promote rapid proliferation
Yangming Wang et al.
Nature Genetics 40, 1478–1483
(December 2008); doi:10.1038/ng.250
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news and views
Cell cycle micromanagement in embryonic stem cells
V Narry Kim
Nature Genetics 40, 1391–1392
(December 2008); doi:10.1038/ng1208-1391
| Full Text (HTML / PDF) |
review
Epigenetic regulation of centromeric chromatin: old dogs, new tricks?
Robin C. Allshire & Gary H. Karpen
Nature Reviews Genetics 9, 923–937
(December 2008); doi:10.1038/nrg2466
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article
Arginine methylation regulates the p53 response
Martin Jansson et al.
Nature Cell Biology 10, 1431–1439
(December 2008); doi:10.1038/ncb1802
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article
Out of the jaws of death: PRMT5 steers p53
Shelley L. Berger
Nature Cell Biology 10, 1389–1390
(December 2008); doi:10.1038/ncb1208-1389
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article
Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV
Kanchan Anand, Antje Schulte, Karin Vogel-Bachmayr, Klaus Scheffzek & Matthias Geyer
Nature Structural & Molecular Biology 15, 1287–1292
(December 2008); doi:10.1038/nsmb.1513
| Summary | Full Text (HTML / PDF) |
November
perspective
Cyclin-dependent kinases and cell-cycle transitions: does one fit all?
Helfrid Hochegger, Shunichi Takeda & Tim Hunt
Nature Reviews Molecular Cell Biology 9, 910–916
(November 2008); doi:10.1038/nrm2510
| Summary | Full Text (HTML / PDF) |
October
letter
Control of plant germline proliferation by SCFFBL17 degradation of cell cycle inhibitors
Hyo Jung Kim et al.
Nature 455, 1134–1137
(23 October 2008); doi:10.1038/nature07289
| Summary | Full Text (HTML / PDF) |
review
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
Martin F. Lavin
Nature Reviews Molecular Cell Biology 9, 759–769
(October 2008); doi:10.1038/nrm2514
| Summary | Full Text (HTML / PDF) |
letter
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas, Felipe Cortés-Ledesma, Alessandro A. Sartori, Andrés Aguilera & Stephen P. Jackson
Nature 455, 689–692
(2 October 2008); doi:10.1038/nature07215
| Summary | Full Text (HTML / PDF) |
September
article
A ribosomal protein L23-nucleophosmin circuit coordinates Miz1 function with cell growth
Michael Wanzel et al.
Nature Cell Biology 10, 1051–1061
(25 September 2008); doi:10.1038/ncb1764
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letter
Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression
Zheng Fu et al.
Nature Cell Biology 10, 1076–1082
(25 September 2008); doi:10.1038/ncb1767
| Summary | Full Text (HTML / PDF) |
review
Cellular mechanisms of tumour suppression by the retinoblastoma gene
Deborah L. Burkhart & Julien Sage
Nature Reviews Cancer 8, 671–682
(September 2008); doi:10.1038/nrc2399
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article
The HP1–p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells
Jean-Pierre Quivy, Annabelle Gérard, Adam J L Cook, Danièle Roche & Geneviève Almouzni
Nature Structural & Molecular Biology 15, 972–979
(September 2008) doi:10.1038/nsmb.1470
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letter
Ripples from neighbouring transcription
Miki Ebisuya, Takuya Yamamoto, May Nakajima & Eisuke Nishida
Nature Cell Biology 10, 1106–1113
(September 2008); doi:10.1038/ncb1771
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news and views
Non-coding RNA transcription: turning on neighbours
Piero Carninci
Nature Cell Biology 10, 1023–1024
(September 2008); doi:10.1038/ncb0908-1023
| Full Text (HTML / PDF) |
review
Conserved functions of the pRB and E2F families
Sander van den Heuvel & Nicholas J. Dyson
Nature Reviews Molecular Cell Biology 9, 713–724
(September 2008); doi:10.1038/nrm2469
| Summary | Full Text (HTML / PDF) |
perspective
Tailoring to RB: tumour suppressor status and therapeutic response
Erik S. Knudsen & Karen E. Knudsen
Nature Reviews Cancer 8, 714–724
(September 2008); doi:10.1038/nrc2401
| Summary | Full Text (HTML / PDF) |
letter
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
Libor Macůrek et al.
Nature 455, 119–123
(04 September 2008); doi:10.1038/nature07185
| Summary | Full Text (HTML / PDF) |
letter
The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
Min Li et al.
Nature Cell Biology 10, 1083–1089
(September 2008); doi:10.1038/ncb1768
| Summary | Full Text (HTML / PDF) |
August
article
The regulated assembly of a PKCε complex controls the completion of cytokinesis
Adrian T. Saurin et al.
Nature Cell Biology 10, 891–901
(August 2008); doi:10.1038/ncb1749
| Summary | Full Text (HTML / PDF) |
letter
IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade
Hisashi Nojima et al.
Nature Cell Biology 10, 971–978
(August 2008); doi:10.1038/ncb1757
| Summary | Full Text (HTML / PDF) |
review
Single-strand break repair and genetic disease
Keith W. Caldecott
Nature Reviews Genetics 9, 619–631
(August 2008); doi:10.1038/nrg2380
| Summary | Full Text (HTML / PDF) |
article
A mechanism for asymmetric segregation of age during yeast budding
Zhanna Shcheprova, Sandro Baldi, Stephanie Buvelot Frei, Gaston Gonnet & Yves Barral
Nature 454, 728–734
(7 August 2008); doi:10.1038/nature07212
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news and views
Cell biology: A molecular age barrier
Matt Kaeberlein
Nature 454, 709–710
(7 August 2008); doi:10.1038/454709a
| Full Text (HTML / PDF) |
review
ATR: an essential regulator of genome integrity
Karlene A. Cimprich & David Cortez
Nature Reviews Molecular Cell Biology 9, 616–627
(August 2008); doi:10.1038/nrm2450
| Summary | Full Text (HTML / PDF) |
July
letter
Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations
Kihoon Lee, Yu Zhang & Sang Eun Lee
Nature 454, 543–546
(24 July 2008); doi:10.1038/nature07054
| Summary | Full Text (HTML / PDF) |
review
Mediators of reprogramming: transcription factors and transitions through mitosis
Dieter Egli, Garrett Birkhoff & Kevin Eggan
Nature Reviews Molecular Cell Biology 9, 505–516
(July 2008); doi:10.1038/nrm2439
| Summary | Full Text (HTML / PDF) |
article
Positive feedback of G1 cyclins ensures coherent cell cycle entry
Jan M. Skotheim, Stefano Di Talia, Eric D. Siggia & Frederick R. Cross
Nature 454, 291–296
(17 July 2008); doi:10.1038/nature07118
| Summary | Full Text (HTML / PDF) |
letter
Positive feedback sharpens the anaphase switch
Liam J. Holt, Andrew N. Krutchinsky & David O. Morgan
Nature 454, 353–357
(17 July 2008); doi:10.1038/nature07050
| Summary | Full Text (HTML / PDF) |
news and views
Systems biology: On the cell cycle and its switches
Silvia D. M. Santos & James E. Ferrell
Nature 454, 288–289
(17 July 2008); doi:10.1038/454288a
| Full Text (HTML / PDF) |
article
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
Irene García-Higuera et al.
Nature Cell Biology 10, 802–811
(July 2008); doi:10.1038/ncb1742
| Summary | Full Text (HTML / PDF) |
news and views
Cdh1: a master G0/G1 regulator
Jeffrey R. Skaar & Michele Pagano
Nature Cell Biology 10, 755–757
(July 2008); doi:10.1038/ncb0708-755
| Full Text (HTML / PDF) |
review
Living on a break: cellular senescence as a DNA-damage response
Fabrizio d'Adda di Fagagna
Nature Reviews Cancer 8, 512–522
(July 2008); doi:10.1038/nrc2440
| Summary | Full Text (HTML / PDF) |
article
Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR
Melanie Winter et al.
Nature Cell Biology 10, 812–824
(July 2008); doi:10.1038/ncb1743
| Summary | Full Text (HTML / PDF) |
June
article
Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle
Karen Crasta, Hong Hwa Lim, Thomas H. Giddings, Jr, Mark Winey & Uttam Surana
Nature Cell Biology 10, 665–675
doi:10.1038/ncb1729
| Summary | Full Text (HTML / PDF) |
article
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity
Alessia Montagnoli et al.
Nature Chemical Biology 4, 357–365
(June 2008); doi:10.1038/nchembio.90
| Summary | Full Text (HTML / PDF) |
news and views
Stopping replication, at the beginning
Peter K Jackson
Nature Chemical Biology 4, 331–332
(June 2008); doi:10.1038/nchembio0608-331
| Full Text (HTML / PDF) |
letter
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient
Brian G. Fuller et al.
Nature 453, 1132–1136
(19 June 2008); doi:10.1038/nature06923
| Summary | Full Text (HTML / PDF) |
letter
p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation
Maria Emanuela Cuomo et al.
Nature Cell Biology 10, 723–730
(June 2008); doi:10.1038/ncb1735
| Summary | Full Text (HTML / PDF) |
review
Spatial and temporal coordination of mitosis by Ran GTPase
Paul R. Clarke & Chuanmao Zhang
Nature Reviews Molecular Cell Biology 9, 464–477
(June 2008); doi:10.1038/nrm2410
| Summary | Full Text (HTML / PDF) |
letter
Global control of cell-cycle transcription by coupled CDK and network oscillators
David A. Orlando et al.
Nature 453, 944–947
(12 June 2008); doi:10.1038/nature06955
| Summary | Full Text (HTML / PDF) |
review
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer
David Frescas & Michele Pagano
Nature Reviews Cancer 8, 438–449
(June 2008); doi:10.1038/nrc2396
| Summary | Full Text (HTML / PDF) |
May
letter
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
Derek J. Richard et al.
Nature 453, 677–681
(29 May 2008); doi:10.1038/nature06883
| Summary | Full Text (HTML / PDF) |
letter
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response
Nabieh Ayoub, Anand D. Jeyasekharan, Juan A. Bernal & Ashok R. Venkitaraman
Nature 453, 682–686
(29 May 2008); doi:10.1038/nature06875
| Summary | Full Text (HTML / PDF) |
review
Mechanisms of asymmetric cell division: flies and worms pave the way
Pierre Gönczy
Nature Reviews Molecular Cell Biology 9, 355–366
(May 2008); doi:10.1038/nrm2388
| Summary | Full Text (HTML / PDF) |
April
article
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Cai-Guang Yang et al.
Nature 452, 961–965
(24 April 2008); doi:10.1038/nature06889
| Summary | Full Text (HTML / PDF) |
letter
A deadenylation negative feedback mechanism governs meiotic metaphase arrest
Eulàlia Belloc & Raúl Méndez
Nature 452, 1017–1021
(24 April 2008); doi:10.1038/nature06809
| Summary | Full Text (HTML / PDF) |
letter
Functional interaction between FOXO3a and ATM regulates DNA damage response
Wen-Bin Tsai, Young Min Chung, Yoko Takahashi, Zhaohui Xu & Mickey C.-T. Hu
Nature Cell Biology 10, 460–467
(April 2008); doi:10.1038/ncb1709
| Summary | Full Text (HTML / PDF) |
letter
A bistable Rb–E2F switch underlies the restriction point
Guang Yao, Tae Jun Lee, Seiichi Mori, Joseph R. Nevins & Lingchong You
Nature Cell Biology 10, 476–482
(April 2008); doi:10.1038/ncb1711
| Summary | Full Text (HTML / PDF) |
letter
Securin regulates entry into M-phase by modulating the stability of cyclin B
Petros Marangos & John Carroll
Nature Cell Biology 10, 445–451
(April 2008); doi:10.1038/ncb1707
| Summary | Full Text (HTML / PDF) |
news and views
Securin' M-phase entry
Mark J. Solomon & Janet L. Burton
Nature Cell Biology 10, 381–383
(April 2008); doi:10.1038/ncb0408-381
| Full Text (HTML / PDF) |
review
Cell-division inhibitors: new insights for future antibiotics
Rowena L. Lock & Elizabeth J. Harry
Nature Reviews Drug Discovery 7, 324–338
(April 2008); doi:10.1038/nrd2510
| Summary | Full Text (HTML / PDF) |
letter
Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation
Daniel R. Gestaut et al.
Nature Cell Biology 10, 407–414
(April 2008); doi:10.1038/ncb1702
| Summary | Full Text (HTML / PDF) |
news and views
Dam1 complexes go it alone on disassembling microtubules
Melissa K. Gardner & David J. Odde
Nature Cell Biology 10, 379–381
(April 2008); doi:10.1038/ncb0408-379
| Full Text (HTML / PDF) |
review
Regulation of DNA repair throughout the cell cycle
Dana Branzei & Marco Foiani
Nature Reviews Molecular Cell Biology 9, 297–308
(April 2008); doi:10.1038/nrm2351
| Summary | Full Text (HTML / PDF) |
article
Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast
Alberto Sanchez-Diaz et al.
Nature Cell Biology 10, 395–406
(April 2008); doi:10.1038/ncb1701
| Summary | Full Text (HTML / PDF) |
March
letter
Control of chromosome stability by the β-TrCP–REST–Mad2 axis
Daniele Guardavaccaro et al.
Nature 452, 365–369
(20 March 2008); doi:10.1038/nature06641
| Summary | Full Text (HTML / PDF) |
letter
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
Thomas F. Westbrook et al.
Nature 452, 370–374
(20 March 2008); doi:10.1038/nature06780
| Summary | Full Text (HTML / PDF) |
article
Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis
Miki Shinohara, Steve D Oh, Neil Hunter & Akira Shinohara
Nature Genetics 40, 299–309
(March 2008); doi:10.1038/ng.83
| Summary | Full Text (HTML / PDF) |
news and views
Division of labor among meiotic genes
Luke E Berchowitz & Gregory P Copenhaver
Nature Genetics 40, 266–267
(March 2008); doi:10.1038/ng0308-266
| Summary | Full Text (HTML / PDF) |
letter
A skin microRNA promotes differentiation by repressing 'stemness'
Rui Yi, Matthew N. Poy, Markus Stoffel & Elaine Fuchs
Nature 452, 225–229
(13 March 2008); doi:10.1038/nature06642
| Summary | Full Text (HTML / PDF) |
letter
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
Arthur P. Young et al.
Nature Cell Biology 10, 361–369
(March 2008); doi:10.1038/ncb1699
| Summary | Full Text (HTML / PDF) |
letter
Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
Edward Owusu-Ansah, Amir Yavari, Sudip Mandal & Utpal Banerjee
Nature Genetics 40, 356–361
(March 2008); doi:10.1038/ng.2007.50
| Summary | Full Text (HTML / PDF) |
article
Dimorphic effects of Notch signaling in bone homeostasis
Feyza Engin et al.
Nature Medicine 14, 299–305
(March 2008); doi:10.1038/nm1712
| Summary | Full Text (HTML / PDF) |
article
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
Matthew J Hilton et al.
Nature Medicine 14, 306–314
(March 2008); doi:10.1038/nm1716
| Summary | Full Text (HTML / PDF) |
letter
Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint
Mariarosaria Musarò, Laura Ciapponi, Barbara Fasulo, Maurizio Gatti & Giovanni Cenci
Nature Genetics 40, 362–366
(March 2008); doi:10.1038/ng.2007.64
| Summary | Full Text (HTML / PDF) |
February
letter
Gamete formation without meiosis in Arabidopsis
Maruthachalam Ravi, Mohan P. A. Marimuthu & Imran Siddiqi
Nature 451, 1121–1124
(28 February 2008); doi:10.1038/nature06557
| Summary | Full Text (HTML / PDF) |
news and views
Biotechnology: A hold on plant meiosis
Peter J. van Dijk
Nature 451, 1063–1064
(28 February 2008); doi:10.1038/4511063a
| Full Text (HTML / PDF) |
review
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
Keith W. Orford & David T. Scadden
Nature Reviews Genetics 9, 115–128
(February 2008); doi:10.1038/nrg2269
| Summary | Full Text (HTML / PDF) |
article
A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
Aude Dupré et al.
Nature Chemical Biology 4, 119–125
(February 2008); doi:10.1038/nchembio.63
| Summary | Full Text (HTML / PDF) |
news and views
Small molecule versus DNA repair nanomachine
James T Stivers
Nature Chemical Biology 4, 86–88
(February 2008); doi:10.1038/nchembio0208-86
| Full Text (HTML / PDF) |
letter
Cell cycle control of centromeric repeat transcription and heterochromatin assembly
Ee Sin Chen, Ke Zhang, Estelle Nicolas, Hugh P. Cam, Martin Zofall & Shiv I. S. Grewal
Nature 451, 734–737
(7 February 2008); doi:10.1038/nature06561
| Summary | Full Text (HTML / PDF) |
letter
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling
Elen Griffith et al.
Nature Genetics 40, 232–236
(February 2008); doi:10.1038/ng.2007.80
| Summary | Full Text (HTML / PDF) |
January
letter
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis
Daijiro Konno et al.
Nature Cell Biology 10, 93–101
(January 2008); doi:10.1038/ncb1673
| Summary | Full Text (HTML / PDF) |
review
Molecular architecture of the kinetochore–microtubule interface
Iain M. Cheeseman & Arshad Desai
Nature Reviews Molecular Cell Biology 9, 33–46
(January 2008); doi:10.1038/nrm2310
| Summary | Full Text (HTML / PDF) |
news and views
IP7 guards the CDK gate
John D York & Daniel J Lew
Nature Chemical Biology 4, 16–17
(January 2008); doi:10.1038/nchembio0108-16
| Full Text (HTML / PDF) |
news and views
DNA damage: ubiquitin marks the spot
Eric J Bennett & J Wade Harper
Nature Structural & Molecular Biology 15, 20–22
(January 2008); doi:10.1038/nsmb0108-20
| Full Text (HTML / PDF) |
article
Molecular basis of cyclin–CDK–CKI regulation by reversible binding of an inositol pyrophosphate
Young-Sam Lee, Kexin Huang, Florante A Quiocho & Erin K O'Shea
Nature Chemical Biology 4, 25–32
(January 2008); doi:10.1038/nchembio.2007.52
| Summary | Full Text (HTML / PDF) |
letter
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
Ivan Ahel et al.
Nature 451, 81–85
(3 January 2008); doi:10.1038/nature06420
| Summary | Full Text (HTML / PDF) |
perspective
Survivin, cancer networks and pathway-directed drug discovery
Dario C. Altieri
Nature Reviews Cancer 8, 61–70
(January 2008); doi:10.1038/nrc2293
| Summary | Full Text (HTML / PDF) |
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