Research library: Apoptosis
2008:
| December
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| July
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December
perspective
Autophagic cell death: the story of a misnomer
Guido Kroemer & Beth Levine
Nature Reviews Molecular Cell Biology 9, 1004–1010
(December 2008); doi:10.1038/nrm2529
| Summary | Full Text (HTML / PDF) |
perspective
The genetics of the p53 pathway, apoptosis and cancer therapy
Alexei Vazquez, Elisabeth E. Bond, Arnold J. Levine & Gareth L. Bond
Nature Reviews Drug Discovery 7, 979–987
(December 2008); doi:10.1038/nrd2656
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article
Arginine methylation regulates the p53 response
Martin Jansson et al.
Nature Cell Biology 10, 1431–1439
(December 2008); doi:10.1038/ncb1802
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news and views
Out of the jaws of death: PRMT5 steers p53
Shelley L. Berger
Nature Cell Biology 10, 1389–1390
(December 2008); doi:10.1038/ncb1208-1389
| Full Text (HTML / PDF) |
review
Double-edged swords as cancer therapeutics: simultaneously targeting p53 and NF-κB pathways
Anwesha Dey, Vinay Tergaonkar & David P. Lane
Nature Reviews Drug Discovery 7, 1031–1040
(December 2008); doi:10.1038/nrd2759
| Summary | Full Text (HTML / PDF) |
review
Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
Avi Ashkenazi
Nature Reviews Drug Discovery 7, 1001–1012
(December 2008); doi:10.1038/nrd2637
| Summary | Full Text (HTML / PDF) |
letter
Regulation of the Drosophila apoptosome through feedback inhibition
Peter J. Shapiro, Hans H. Hsu, Heekyung Jung, Edith S. Robbins & Hyung Don Ryoo
Nature Cell Biology 10, 1440–1446
(December 2008); doi:10.1038/ncb1803
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news and views
Staying alive: apoptosome feedback inhibition
Hermann Steller
Nature Cell Biology 10, 1387–1388
(December 2008); doi:10.1038/ncb1208-1387
| Full Text (HTML / PDF) |
letter
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
Allyson E. Vaughn & Mohanish Deshmukh
Nature Cell Biology 10, 1477–1483
(December 2008); doi:10.1038/ncb1807
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review
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
Inki Kim, Wenjie Xu & John C. Reed
Nature Reviews Drug Discovery 7, 1013–1030
(December 2008); doi:10.1038/nrd2755
| Summary | Full Text (HTML / PDF) |
review
BCL-2 family antagonists for cancer therapy
Guillaume Lessene, Peter E. Czabotar & Peter M. Colman
Nature Reviews Drug Discovery 7, 989–1000
(December 2008); doi:10.1038/nrd2658
| Summary | Full Text (HTML / PDF) |
November
letter
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
Mads Gyrd-Hansen et al.
Nature Cell Biology 10, 1309-1317 (2008)
(November 2008); doi:10.1038/ncb1789
| Summary | Full Text (HTML / PDF) |
October
review
Phagosome maturation: going through the acid test
Jason M. Kinchen & Kodi S. Ravichandran
Nature Reviews Molecular Cell Biology 9, 781–795
(October 2008); doi:10.1038/nrm2515
| Summary | Full Text (HTML / PDF) |
article
BAX activation is initiated at a novel interaction site
Evripidis Gavathiotis et al.
Nature 455, 1076–1081
(23 October 2008); doi:10.1038/nature07396
| Summary | Full Text (HTML / PDF) |
news and views
Apoptosis: Stabbed in the BAX
Douglas R. Green & Jerry E. Chipuk
Nature 455, 1047–1049
(23 October 2008); doi:10.1038/4551047a
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article
Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3
Xin Geng et al.
Nature Structural & Molecular Biology 15, 1094–1101
(October 2008); doi:10.1038/nsmb.1488
| Summary | Full Text (HTML / PDF) |
review
The TRAIL apoptotic pathway in cancer onset, progression and therapy
Ricky W. Johnstone, Ailsa J. Frew & Mark J. Smyth
Nature Reviews Cancer 8, 782–798
(October 2008); doi:10.1038/nrc2465
| Summary | Full Text (HTML / PDF) |
September
article
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
Maria A Ermolaeva et al.
Nature Immunology 9, 1037–1046
(September 2008); doi:10.1038/ni.1638
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article
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
Yelena L Pobezinskaya et al.
Nature Immunology 9, 1047–1054
(September 2008); doi:10.1038/ni.1639
| Summary | Full Text (HTML / PDF) |
news and views
A birthday gift for TRADD
Gioacchino Natoli & Liv M I Austenaa
Nature Immunology 9, 1015–1016
(September 2008); doi:10.1038/ni0908-1015
| Full Text (HTML / PDF) |
August
perspective
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
Stefan Schütze, Vladimir Tchikov & Wulf Schneider-Brachert
Nature Reviews Molecular Cell Biology 9, 655–662
(August 2008); doi:10.1038/nrm2430
| Summary | Full Text (HTML / PDF) |
progress
New roles for TIM family members in immune regulation
Vijay K. Kuchroo, Valerie Dardalhon, Sheng Xiao & Ana C. Anderson
Nature Reviews Immunology 8, 577–580
(August 2008); doi:10.1038/nri2366
| Summary | Full Text (HTML / PDF) |
July
letter
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
Nilkantha Sen et al.
Nature Cell Biology 10, 866–873
(July 2008); doi:10.1038/ncb1747
| Summary | Full Text (HTML / PDF) |
review
Cytochrome c: functions beyond respiration
Yong-Ling P. Ow, Douglas R. Green, Zhenyue Hao & Tak W. Mak
Nature Reviews Molecular Cell Biology 9, 532–542
(July 2008); doi:10.1038/nrm2434
| Summary | Full Text (HTML / PDF) |
review
Mitochondrial fragmentation in neurodegeneration
Andrew B. Knott, Guy Perkins, Robert Schwarzenbacher & Ella Bossy-Wetzel
Nature Reviews Neuroscience 9, 505–518
(July 2008); doi:10.1038/nrn2417
| Summary | Full Text (HTML / PDF) |
letter
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
Nature 454, 232–235
(10 July 2008); doi:10.1038/nature07006
| Summary | Full Text (HTML / PDF) |
June
letter
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B
Xiaoling Tang et al.
Nature Cell Biology 10, 698–706
(June 2008); doi:10.1038/ncb1732
| Summary | Full Text (HTML / PDF) |
letter
p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation
Maria Emanuela Cuomo et al.
Nature Cell Biology 10, 723–730
(June 2008); doi:10.1038/ncb1735
| Summary | Full Text (HTML / PDF) |
May
article
Identification of RIP1 kinase as a specific cellular target of necrostatins
Alexei Degterev et al.
Nature Chemical Biology 5, 313–321
(May 2008); doi:10.1038/nchembio.83
| Summary | Full Text (HTML / PDF) |
letter
A pathway for phagosome maturation during engulfment of apoptotic cells
Jason M. Kinchen et al.
Nature Cell Biology 10, 556–566
(May 2008); doi:10.1038/ncb1718
| Summary | Full Text (HTML / PDF) |
letter
Imaging of Rab5 activity identifies essential regulators for phagosome maturation
Masahiro Kitano, Michio Nakaya, Takeshi Nakamura, Shigekazu Nagata & Michiyuki Matsuda
Nature 453, 241–245
(8 May 2008); doi:10.1038/nature06857
| Summary | Full Text (HTML / PDF) |
analysis
Transcriptional control of human p53-regulated genes
Todd Riley, Eduardo Sontag, Patricia Chen & Arnold Levine
Nature Reviews Molecular Cell Biology 9, 402–412
(May 2008); doi:10.1038/nrm2395
| Summary | Full Text (HTML / PDF) |
review
NLRs at the intersection of cell death and immunity
Jenny P.-Y. Ting, Stephen B. Willingham & Daniel T. Bergstralh
Nature Reviews Immunology 8, 372–379
(May 2008); doi:10.1038/nri2296
| Summary | Full Text (HTML / PDF) |
article
CD3-specific antibody-induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells
Sylvain Perruche, Pin Zhang, Yongzhong Liu, Philippe Saas, Jeffrey A Bluestone & WanJun Chen
Nature Medicine 14, 528–535
(May 2008); doi:10.1038/nm1749
| Summary | Full Text (HTML / PDF) |
review
Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival
H. Llewelyn Roderick & Simon J. Cook
Nature Reviews Cancer 8, 361–375
(May 2008); doi:10.1038/nrc2374
| Summary | Full Text (HTML / PDF) |
review
Expansion and evolution of cell death programmes
Alexei Degterev & Junying Yuan
Nature Reviews Molecular Cell Biology 9, 378–390
(May 2008); doi:10.1038/nrm2393
| Summary | Full Text (HTML / PDF) |
April
brief communication
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Ian M Morison et al.
Nature Genetics 40, 387–389
(April 2008); doi:10.1038/ng.103
| Summary | Full Text (HTML / PDF) |
news and views
Re-examining the role of cytochrome c in cell death
Eric Solary, Fabrizio Giordanetto & Guido Kroemer
Nature Genetics 40, 379–380
(April 2008); doi:10.1038/ng0408-379
| Summary | Full Text (HTML / PDF) |
review
How dying cells alert the immune system to danger
Hajime Kono & Kenneth L. Rock
Nature Reviews Immunology 8, 279–289
(April 2008); doi:10.1038/nri2215
| Summary | Full Text (HTML / PDF) |
March
review
Apoptosis: controlled demolition at the cellular level
Rebecca C. Taylor, Sean P. Cullen & Seamus J. Martin
Nature Reviews Molecular Cell Biology 9, 231–241
(March 2008); doi:10.1038/nrm2312
| Summary | Full Text (HTML / PDF) |
article
Transcription factor FOXO3a controls the persistence of memory CD4+ T cells during HIV infection
Julien van Grevenynghe et al.
Nature Medicine 14, 266–274
(March 2008); doi:10.1038/nm1728
| Summary | Full Text (HTML / PDF) |
letter
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
Jyh-Rong Chao, Evan Parganas, Kelli Boyd, Cheol Yi Hong, Joseph T. Opferman & James N. Ihle
Nature 452, 98–102
(6 March 2008); doi:10.1038/nature06604
| Summary | Full Text (HTML / PDF) |
February
article
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N Danial et al.
Nature Medicine 14, 144–153
(February 2008); doi:10.1038/nm1717
| Summary | Full Text (HTML / PDF) |
review
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
Anthony G. Letai
Nature Reviews Cancer 8, 121–132
(February 2008); doi:10.1038/nrc2297
| Summary | Full Text (HTML / PDF) |
letter
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim, Junjie Chen & Zhenkun Lou
Nature 451, 583–586
(31 January 2008); doi:10.1038/nature06500
| Summary | Full Text (HTML / PDF) |
letter
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu
Nature 451, 587–590
(31 January 2008); doi:10.1038/nature06515
| Summary | Full Text (HTML / PDF) |
January
review
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle & Andreas Strasser
Nature Reviews Molecular Cell Biology 9, 47–59
(January 2008); doi:10.1038/nrm2308
| Summary | Full Text (HTML / PDF) |
review
Immunological aspects of cancer chemotherapy
Laurence Zitvogel, Lionel Apetoh, François Ghiringhelli & Guido Kroemer
Nature Reviews Immunology 8, 59–73
(January 2008); doi:10.1038/nri2216
| Summary | Full Text (HTML / PDF) |
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